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目的:分析影响供精人工授精成功率的相关因素。方法:回顾性分析2007年4月~2008年4月期间在该院行供精人工授精(artificial insemination with donor semen AID)的840例妇女,共1 478个周期。分析年龄、输卵管通畅情况、子宫内膜类型、AID手术方式与AID成功率的关系。结果:①年龄越大,AID成功率越低,大于35岁的不孕妇女AID成功率明显下降。②输卵管欠畅,AID)成功率明显下降。③子宫内膜A型的病例AID成功率高于其他类型的病例。④宫颈内和宫腔内人工授精的成功率差异无统计学意义(P>0.05)。结论:不孕妇女的年龄、输卵管治疗史及子宫内摸类型是影响AID治疗成功率的重要因素,在无宫颈因素的妇女中,宫颈内人工授精较宫腔内人工授精操作更简便,成本低,且成功率相似,应该考虑首选宫颈内人工授精。
Objective: To analyze the relevant factors that influence the success rate of artificial insemination. Methods: A retrospective analysis of 840 women with artificial insemination with donor semen AID from April 2007 to April 2008 in a total of 1 478 cycles was performed. Analysis of age, tubal patency, endometrial types, AID surgical methods and the success rate of AID. Results: ① The higher the age, the lower the success rate of AID. The success rate of AID in infertile women over 35 years old decreased significantly. ② fallopian tube, AID) success rate decreased significantly. ③ endometrial A-type cases AID success rate higher than other types of cases. ④ There was no significant difference in the success rate of intra-uterine and intra-uterine insemination (P> 0.05). CONCLUSIONS: The age of infertile women, the history of tubal treatment and the type of intrauterine infection are important factors that influence the success rate of AID treatment. Among women without cervical factors, intra-cervical artificial insemination is more convenient and cost-effective than intrauterine insemination , And the success rate is similar, we should consider the preferred intrauterine insemination.