论文部分内容阅读
目的 探讨卵巢外原发腹膜浆液性乳头状癌 (EPSPC)的临床和治疗特点及预后。方法回顾性分析 12例EPSPC与 4 5例Ⅲ、Ⅳ期卵巢浆液性乳头状癌 (OPSC)的临床和随访资料 ,比较其临床及治疗特点、对一线化疗药物的敏感性及生存时间。结果 EPSPC与OPSC两组的症状、体征、CA12 5水平、无瘤期、复发时间、对一线化疗药物的反应及生存时间差异无统计学意义 ,而EPSPC组的完全缓解率 (2 5 .0 % )与OPSC组 (91.8% )比较 ,显著降低 (P <0 .0 1)。结论 EPSPC与OPSC临床过程类似 ,当治疗手段相同时 ,对一线化疗药物的敏感性及生存时间相近。
Objective To investigate the clinical features and prognosis of primary peritoneal serous papillary carcinoma (EPSPC) outside the ovary. Methods The clinical and follow - up data of 12 cases of EPSPC and 45 cases of stage Ⅲ and Ⅳ ovarian serous papillary carcinoma (OPSC) were retrospectively analyzed. Their clinical and therapeutic characteristics, sensitivity to first - line chemotherapeutic drugs and their survival time were compared. Results There were no significant differences in the symptoms, signs, CA125 levels, tumor-free period, recurrence time, response to first-line chemotherapy drugs and survival time in EPSPC and OPSC groups, while the complete response rate in EPSPC group was 25.0% ) Was significantly lower than the OPSC group (91.8%) (P <0.01). Conclusions EPSPC is similar to the clinical course of OPSC. When the treatment is the same, the sensitivity and survival time of the first-line chemotherapy drugs are similar.