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补体对免疫沉淀的抑制作用 ( PC)为补体的一种新功能。为了研究 PC及补体成分在骨关节结核发病中的作用 ,采用结核杆菌特异性抗原与相应抗体对骨关节结核患者的 PC进行了检测 ,并同时测定血清补体成分 C3、C4。结果 ,患者组 PC为0 .35± 0 .0 8,与正常对照组 (0 .45± 0 .0 6 )相比显著降低 (P<0 .0 1) ,C3亦明显低于对照组 (P<0 .0 5 ) ,C4有所降低但无显著性意义。表明 PC降低在骨关节结核发病中有一定作用。 PC降低与补体成分减少有一定关系。
The inhibitory effect of complement on immunoprecipitation (PC) is a new function of complement. In order to study the role of PC and complement components in the pathogenesis of bone and joint tuberculosis, the PC of patients with bone and joint tuberculosis was detected by using the specific antigens of Mycobacterium tuberculosis and corresponding antibodies, and the serum complement components C3 and C4 were measured simultaneously. As a result, the patient group PC was 0.35 ± 0.08, significantly lower than that of the normal control group (0.45 ± 0.06) (P <0.01), and C3 was also significantly lower than that of the control group P <0. 05), C4 decreased but no significant significance. PC reduction in the incidence of bone and joint tuberculosis have a role. Decreased PC and complement components have a certain relationship.