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目的 确定尿激酶在治疗结核性包裹性胸腔积液的作用。方法 在规则抗痨下 ,对 2 1例结核性包裹性胸腔积液的病人胸腔内注入尿激酶 50 0 0 0U +异烟肼 0 .3g/日 ,1 4例应用胸腔内注入强的松龙1 2 5mg+异烟肼 0 .3g/日作对照。平均引流天数为 5天。结果 治疗组 2 1例中 ,94 3 % ( 1 9/2 1 )达到完全好转 ,4 2 9% ( 6/1 4 )达到部分好转 ,1 3 .4 % ( 3 /1 4 )无效。结论 在规则抗痨治疗下 ,配合胸腔内注入尿激酶治疗结核性包裹性胸腔积液可增加引流量 ,减轻胸膜厚度 ,并改善肺功能。
Objective To determine the role of urokinase in the treatment of tuberculous pleural effusion. Methods Thirty-two cases of tuberculous pleural effusion were injected intrathoracically with 0.5 × 10 uU of isoniazid and 0.3 g / 1 2 5mg + isoniazid 0 .3g / day as a control. The average number of days of drainage is 5 days. Results Among the 21 patients in the treatment group, 94 3% (1 9/2 1) achieved complete improvement, 4 2 9% (6/1 4) achieved partial improvement and 13.4% (3/1 4) failed. Conclusion In the treatment of regular anti-tuberculosis, intrapleural injection of urokinase in the treatment of tuberculous pleural effusion can increase drainage, reduce pleural thickness, and improve lung function.