硝基呋喃类药物是人工合成的具有5-硝基呋喃基本结构的广谱抗菌药物,对光敏感,代谢快速,原药及其在动物体内残留的代谢产物有致畸、致突变和致癌的危险.出于安全性考虑,欧美等发达国家及我国先后颁布了禁止使用该类兽药的禁令.目前对硝基呋喃类代谢物的检测,国际上通用的方法是经2-硝基苯甲醛衍生化后用液相色谱-串联质谱法测 Nitrofurans are synthetic broad-spectrum antibacterial drugs with the basic structure of 5-nitrofuran. They are sensitive to light and rapidly metabolized. The original drugs and their metabolites left in animals are teratogenic, mutagenic and carcinogenic For safety reasons, the developed countries such as Europe and the United States and our country have successively promulgated a ban on the use of such veterinary drugs.At present, the common method for the detection of nitrofurane metabolites is to derivatize 2-nitrobenzaldehyde After using liquid chromatography - tandem mass spectrometry