抑郁障碍对心肌梗死患者的发生、发展及预后存在负性影响。抑郁障碍可通过影响生活方式、血小板活性、内皮功能,引起炎性反应、自主神经功能障碍,加重心功能不全等方面引起心肌梗死患者病残、病死率增加。对于合并抑郁障碍的心肌梗死患者进行临床干预非常重要,心理治疗、药物治疗可能可以改善此类患者预后。 Depression has a negative impact on the occurrence, development and prognosis of patients with myocardial infarction. Depression can affect the lifestyle, platelet activity, endothelial function, causing inflammatory reactions, autonomic dysfunction, increased cardiac dysfunction and other aspects of sick patients with myocardial infarction, mortality increased. Clinical intervention in patients with myocardial infarction complicated with depression is very important, psychological treatment, drug treatment may improve the prognosis of such patients.