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目的：探讨单纯性下肢静脉曲张中医辨证分型与大隐静脉超声观察指标之间的相关性。方法将132例单纯性下肢静脉曲张患者分为脉络湿邪阻滞证组、脉络湿邪瘀阻证组、脉络湿毒瘀热证组,分别对3组患者进行超声检查,比较3组大隐静脉近心段管径、返流峰值速度、返流时间。结果3组大隐静脉近心段管径比较差异有统计学意义( P<0．001),3组中每2组管径比较差异均有统计学意义(P<0．05),大隐静脉近心段管径从粗到细的顺序为：脉络湿毒瘀热证组、脉络湿邪瘀阻证组、脉络湿邪阻滞证组。3组返流峰值速度比较差异有统计学意义( P<0．001),3组中每2组返流峰值速度比较差异均有统计学意义(P<0．05),大隐静脉近心段的返流峰值速度从高到低的顺序为：脉络湿毒瘀热证组、脉络湿邪瘀阻证组、脉络湿邪阻滞证组。3组返流时间比较差异有统计学意义( P<0．001),3组中每2组返流时间比较差异均有统计学意义( P<0．05),大隐静脉近心段的返流时间从长到短的顺序为：脉络湿毒瘀热证组、脉络湿邪瘀阻证组、脉络湿邪阻滞证组。结论大隐静脉超声观察指标与单纯性下肢静脉曲张的中医证型具有一定的相关性,可为单纯性下肢静脉曲张辨证分型提供客观依据。“,”Objective To explore the correlation between Chinese medicine syndrome differentiation types of simplex varicose veins in lower extremity and great saphenous vein ultrasound indexes. Methods 132 patients suffering simplex varicose veins of lower extremity were divided into 3 groups:dampness blocking channels syndrome, dampness and blood stasis blocking channels syndrome, dampness and stagnant heat syndrome. Great saphenous vein in recent period of pipe diameter, peak reflux velocity ( PRV ) and reflux time ( RT) were compared among the three groups. Results There was significant difference of great saphenous vein in recent period of pipe diameter among three groups ( P<0. 001 ) , and significance difference was also existed between each two groups (P<0. 05). The sequence of great saphenous vein in recent period of pipe diameter from thick to thin was: dampness and stagnant heat syndrome, dampness and blood stasis blocking channels syndrome, dampness blocking channels syndrome. There was significant difference of PRV among three groups ( P<0. 001 ) , and significant difference was alsoexisted between each two groups (P<0. 05). The sequence of PRV from high to low was:dampness and stagnant heat syndrome, dampness and blood stasis blocking channels syndrome, dampness blocking channels syndrome. There was significant difference of RT among three groups ( P < 0. 001 ) , and significant difference was also existed between each two groups ( P <0. 05 ) . The sequence of RT from long to short was: dampness and stagnant heat syndrome, dampness and blood stasis blocking channels syndrome, dampness blocking channels syndrome. Conclusion There is correlation between great saphenous vein ultrasound indexes and the syndrome of simplex varicose veins in lower extremity, which could provide evidence for syndrome differentiation of simplex varicose veins in lower extremity.