为了探明小儿恶性淋巴瘤与Ｃ－ｍ ｙｃ 基因的关系，本文采用免疫组化法检测了３３ 例该瘤石蜡切片中Ｃ－ｍ ｙｃ基因的表达水平。结果显示：肿瘤组的Ｃ－ｍ ｙｃ染色阳性率为３９．４％ ，其中，Ｔ细胞型淋巴瘤为１１．１％ ，Ｂ细胞型淋巴瘤和何杰金病均为５０．０％ ；反应性增生组的阳性率仅为８．９％ 。表明Ｃ－ｍ ｙｃ基因的表达与小儿恶性淋巴瘤，特别是与Ｂ细胞型淋巴瘤及何杰金病的发生有一定关系。 In order to explore the relationship between pediatric malignant lymphoma and C-m yc gene, immunohistochemistry was used to detect the expression of C-m yc gene in 33 cases of paraffin sections. The results showed that the positive rate of C-m yc staining was 39.4% in the tumor group, of which, 11.1% of T-cell lymphoma, 50.0% of B-cell lymphoma and Hodgkin’s disease; The positive rate of sexual proliferation group was only 8.9%. It is indicated that the expression of C-m yc gene is related to the occurrence of pediatric malignant lymphoma, especially with B cell lymphoma and Hodgkin’s disease.