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华蟾素是从中华大蟾蜍阴干全皮中提取的水溶性制剂,其有效成分主要是生物硷,还有一定量的氨基酸、还原糖和蟾蜍色胺。近年研究发现有抗癌,升高白细胞,抗过敏,抗呃逆作用,还有纠正心衰,呼吸衰竭作用。现就其临床应用试述如下。 1 治疗慢性乙型肝炎 对慢性乙型肝炎的治疗,迄今尚无特效药物,认为其与机体免疫功能变化,尤其是细胞免疫功能低下或缺陷及乙肝病毒在肝内的持续复制有关。因此,目前对慢性肝炎的治疗主要是抗病毒和免疫调节治疗。华蟾素具有较好的抑制乙肝病毒复制的作用,并具有一定的改善肝脏病理损害作用,还具有较好的细胞免疫调节功能,通过调整机体的细胞免疫功能紊乱状况而达到抑制或清除乙肝病毒的复制,达
Cinobufagin is a water-soluble preparation extracted from the dried whole skin of Bufo bufo gargarizans. Its active ingredients are mainly alkaloids, as well as a certain amount of amino acids, reducing sugars and toadine. In recent years, studies have found that anti-cancer, increased white blood cells, anti-allergy, anti-hiccups, as well as correct heart failure, respiratory failure. Now on its clinical application as follows. 1 treatment of chronic hepatitis B treatment of chronic hepatitis B, there is no specific drug so far that the immune function and its changes, especially cellular immune dysfunction or defects and hepatitis B virus in the liver continued replication. Therefore, the current treatment of chronic hepatitis is mainly antiviral and immunomodulatory treatment. Cinobufotalin has a good effect of inhibiting the replication of hepatitis B virus, and has a certain role in improving liver pathological damage, but also has better cellular immune regulatory function, by adjusting the body’s cellular immune disorders to achieve the suppression or elimination of hepatitis B virus The copy, up