论文部分内容阅读
目的探讨丙泊酚在不同年龄无痛胃镜检查时的用量。方法选择门诊行胃镜检查的患者120例,按年龄分为四组,Ⅰ组(18~40岁),Ⅱ组(40~55岁),Ⅲ组(55~70岁),Ⅳ组(70~85岁),每组30例。记录丙泊酚用量、MAP、HR、RR、SpO2及检查时间。结果Ⅰ、Ⅱ组MAP、HR、RR、SpO2与基础值相比差异无统计学意义,两组丙泊酚用量差异无统计学意义。Ⅲ、Ⅳ组MAP、RR、SpO2与基础值比较有所下降,差异有统计学意义(P<0.05),HR变化不明显;丙泊酚用量明显比Ⅰ、Ⅱ组少,且Ⅳ组比Ⅲ组少,差异有统计学意义(P<0.05)。结论丙泊酚在无痛胃镜检查中的用量,青壮年在2.0mg/kg以上,老年人随着年龄的增大而减少,在2.0mg/kg以下。
Objective To investigate the dosage of propofol in painless gastroscopy at different ages. Methods One hundred and twenty patients undergoing gastroscopy were divided into four groups according to their ages: group Ⅰ (18-40 years), group Ⅱ (40-55 years), group Ⅲ (55-70 years), group Ⅳ (70-70 years) 85 years old), 30 cases in each group. Record the amount of propofol, MAP, HR, RR, SpO2 and examination time. Results There were no significant differences in MAP, HR, RR and SpO2 between group Ⅰ and group Ⅱ, and there was no significant difference between two groups in the dosage of propofol. The levels of MAP, RR and SpO2 in group Ⅲ and Ⅳ decreased compared with the baseline, the difference was statistically significant (P <0.05), the change of HR was not obvious; the dosage of propofol was less than that in group Ⅰ and Ⅱ, and the ratio of Ⅲ Group less, the difference was statistically significant (P <0.05). Conclusion The dosage of propofol in painless gastroscopy is above 2.0 mg / kg in young and middle-aged adults, and decreases with age at 2.0 mg / kg.