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由于内镜止血的发展和H_2受体阻滞剂及某些胃肠激素的应用,胃肠道出血外科治疗的作用已大为减少,本研究针对慢性消化性溃疡和急性胃粘膜病变(AGML)引起的胃十二指肠出血采用持续静脉输注胰泌素制剂(Secrepan),评价其止血效果。病人和方法:37例出血性溃疡(13例慢性消化性溃疡和24例AGML),用Secrepan 持续静脉滴注,开始3天速率为2U/kg·h,后4天为0.5U/kg.h,经鼻-胃管或胃镜证实出血是否停止。止血效果用如下4个等级来评价:极好:治疗开始后36小时内出血停止;良好:治疗开始后36小时至3天之间出血停止;尚
Due to the development of endoscopic hemostasis and the application of H 2 receptor blockers and some gastrointestinal hormones, the role of surgical treatment of gastrointestinal bleeding has been greatly reduced. In this study, chronic peptic ulcer and acute gastric mucosal lesions (AGML) Gastroduodenal hemorrhage caused by continuous intravenous infusion of secretin preparation (Secrepan), to evaluate the hemostatic effect. PATIENTS AND METHODS: Thirty-seven hemorrhagic ulcers (13 with chronic peptic ulcer and 24 with AGML) were treated with continuous infusion of Secrepan at a rate of 2 U / kg · h for 3 days and 0.5 U / kg.h after 4 days , Nasal - gastric tube or gastroscopy to confirm whether the bleeding stopped. The hemostatic effect was evaluated in four grades as follows: Excellent: Bleeding stopped within 36 hours after treatment started; Good: Bleeding stopped between 36 hours and 3 days after the start of treatment; Still