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目的探讨1,25(OH)2D3治疗终末期肾病患者继发性甲状旁腺功能亢进症有效性和安全性。方法分析血液净化中心84例患者服用1,25(OH)2D3、含钙磷结合剂后血钙、磷、钙磷乘积,iPTH变化。结果血钙、磷、钙磷乘积,iPTH发生变化。结论终末期肾病患者合理活性维生素D3等治疗后血钙、磷、钙磷乘积可达到正常动态平衡。
Objective To investigate the efficacy and safety of 1,25 (OH) 2D3 in the treatment of secondary hyperparathyroidism in patients with end-stage renal disease. Methods The blood calcium, phosphorus, calcium and phosphorus products and iPTH in 84 patients with blood purification center after taking 1,25 (OH) 2D3 and calcium-phosphorus binding agents were analyzed. Results Calcium, phosphorus, calcium and phosphorus products, iPTH changes. Conclusions The serum calcium, phosphorus and calcium-phosphorus product of the patients with end-stage renal disease can reach normal homeostasis after the reasonable activity of vitamin D3 and so on.