局灶节段性肾小球硬化(FSGS)是由多种病因引起的,以肾小球节段硬化为病理特征的一组疾病。临床主要表现为蛋白尿,并逐步进展为慢性肾功能不全。FSGS早期虽然肾小球硬化较局限,但存在广泛足突融合,提示足细胞是损伤的主要靶细胞。近年来人们对FSGS病理形态学特征进行了深入的研 Focal segmental glomerulosclerosis (FSGS) is a group of diseases caused by a variety of etiologies, with glomerulosclerosis as a pathological feature. Clinical manifestations of proteinuria, and gradually progress to chronic renal insufficiency. FSGS early although glomerular sclerosis more confined, but there is extensive foot process fusion, suggesting that podocyte injury is the main target cells. In recent years, people conducted a thorough research on the pathological features of FSGS