论文部分内容阅读
目的评价阿司匹林联合缓释型双嘧达莫防治急性缺血性卒中后脑血管缺血事件的临床作用。方法选择2009年2月-2012年1月清苑县人民医院收治的63例急性缺血性卒中患者作为研究对象,根据抗血小板治疗药物使用情况分为A组33例和B组30例,A组采用阿司匹林联合缓释型双嘧达莫治疗,B组仅采用阿司匹林治疗,比较两组对脑血管缺血事件的防治作用。结果 A、B两组治疗后的神经功能缺损评分均明显改善,以A组改善更为明显(P<0.05);随访6个月,A组脑血管缺血事件发生率为3.0%,B组为23.3%,组间差异有统计学意义(P<0.05);两组均无严重不良反应发生。结论阿司匹林联合缓释型双嘧达莫防治急性缺血性卒中后脑血管缺血事件的临床作用显著,能明显改善患者的神经功能,减少脑血管缺血事件的发生,并且安全性好,是临床首选的药物治疗方案之一。
Objective To evaluate the clinical effect of aspirin combined with sustained-release dipyridamole on cerebrovascular ischemia after acute ischemic stroke. Methods Sixty-three patients with acute ischemic stroke admitted to Qingyuan County People’s Hospital from February 2009 to January 2012 were selected and divided into group A (33 cases) and group B (30 cases) according to the use of antiplatelet drugs Group treated with aspirin combined with sustained-release dipyridamole, B group only aspirin treatment, compared two groups of cerebrovascular ischemic events prevention and treatment. Results After treatment, the neurological impairment scores of A and B groups were significantly improved, and the improvement was more obvious in group A (P <0.05). After 6 months of follow-up, the incidence of cerebrovascular ischemic events in group A was 3.0% Was 23.3%, the difference between the groups was statistically significant (P <0.05); no serious adverse reactions occurred in both groups. Conclusion Aspirin combined with sustained-release dipyridamole has a significant clinical effect in preventing and treating ischemic stroke after acute ischemic stroke. It can significantly improve the neurological function and reduce the occurrence of cerebrovascular ischemic events. It is safe and clinically One of the preferred drug treatment options.