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1989年1月至6月分别在北京友谊医院儿科、天坛医院儿科选择新入院1～6岁肺炎病儿65例和在门诊选择28例健康儿童,静脉取血测定其血中维生素A、锌、铜、钙的含量和血清白蛋白及T细胞亚群。实验结果表明,肺炎病儿血清维生素A(36.9±23.2μg/dl)、锌(106.6±31.9μg/dl)的含量明显低于健康儿童(血清维生素A 55.5±18.7μg/dl;锌133.7±30.1μg/dl),有统计学上的差异(P<0.01)。血清铜、铜/锌比值肺炎病儿明显高于健康儿童,两组儿童也有统计学上的差异(P<0.01)。肺炎病儿血中总T细胞和T_R百分数及T_R/T_S比值明显低于健康儿童,两组儿童总T细胞和T_R百分数及T_R/T_S比值均有显著性差异(P<0.05)。血清钙和血清白蛋白含量两组儿童均无显著性差异。本研究结果表明,血清维生A、锌含量肺炎组儿童明显低于健康组儿童,而血清铜含量和铜/锌比值则相反,几种T细胞亚群也有不同。若改善儿童的维生素A和锌的营养状况,可能会减少儿童呼吸道感染性疾病发生的机会。
January 1989 to June in Beijing Friendship Hospital Pediatrics, Tiantan Hospital pediatric choose new admission of children aged 65 to 65 years with pneumonia and outpatient selection of 28 healthy children, venous blood was taken to determine the blood of vitamin A, zinc, Copper, calcium content and serum albumin and T cell subsets. The results showed that the levels of serum vitamin A (36.9 ± 23.2μg / dl) and zinc (106.6 ± 31.9μg / dl) in children with pneumonia were significantly lower than those in healthy children (serum vitamin A 55.5 ± 18.7μg / dl; zinc 133.7 ± 30.1 μg / dl), there was a statistically significant difference (P <0.01). Serum copper, copper / zinc ratio in children with pneumonia was significantly higher than healthy children, there was also a statistically significant difference between the two groups of children (P <0.01). The total T cells and T_R percentage and T_R / T_S ratio in children with pneumonia were significantly lower than those in healthy children. There were significant differences in total T cells, percentage of T_R and T_R / T_S between the two groups (P <0.05). Serum calcium and serum albumin levels in both groups showed no significant difference. The results of this study showed that children with serum vitamin A and zinc content pneumonia group were significantly lower than those in healthy group, while serum copper content and copper / zinc ratio were the opposite, and there were also differences in several T cell subsets. Improving the nutritional status of children’s vitamin A and zinc may reduce the chances of children’s respiratory infections.