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18号染色体三体综合征患者中常见眼眶和眼部异常。本文报道一例此征合并先天性丝带状睑缘粘连(以下简称AFA)。睑缘粘连系指外眦部跟脸的直接联合,可为先天性或后天性者。1881年von Hasner首次报道此种罕见的先天异常AFA,此为上、下睑单个或多个的纤细结缔组织条带的粘连,可发生在上下睑的任何部位,但不在内眦部。用力睁眼时这些丝带可伸长至两倍。此带由灰线发出,向前到睑板腺口,向后到睫毛根部。据报道AFA多并发于腭裂和兔唇,但也见于一系列其它先天异常,如脑积水、脊髓脊膜突出
Eye orbital and ocular abnormalities are common in patients with Chromosomal Trisomy 18. This article reports a case of this syndrome with congenital ribbon-shaped eyelid adhesion (hereinafter referred to as AFA). Eyelid adhesion refers to the Department of the Ministry of the outer straight joint with the face can be congenital or acquired. In 1881 von Hasner for the first time reported this rare congenital anomaly AFA, which is the adhesion of one or more slender connective tissue bands in the upper and lower eyelids, which can occur anywhere in the upper and lower eyelids, but not in the medial part. These ribbons can be lengthened to twice as long as the eyes open. This band is issued by the gray line, forward to the meibomian gland mouth, back to the roots of eyelashes. It is reported that AFA mostly complicated by cleft lip and cleft lip, but also found in a series of other congenital anomalies, such as hydrocephalus, meningocele