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目的对比研究蓝芩口服液与匹多莫德片对手足口病普通患儿的治疗效果。方法 300例手足口病普通患儿,随机分为蓝芩组、匹多组和联合治疗组,每组100例,在常规抗病毒、退热等对症治疗基础上,分别给予蓝芩口服液、匹多莫德片、蓝芩口服液联合匹多莫德片治疗,观察三组患儿的治疗效果。结果蓝芩口服液治疗组与匹多莫德片治疗组的退热时间、疱疹消退时间、手足皮疹消退时间及治疗总有效率比较,差异无统计学意义(P>0.05);而联合治疗组的退热时间、疱疹消退时间、手足皮疹消退时间及治疗总有效率与单一治疗组对比其差异均有统计学意义(P<0.05),表明两种药物联合治疗能明显促进退热及加快疱疹和皮疹的消退,并提高总有效率。两种药物均未见明显不良反应。结论采用蓝芩口服液和匹多莫德片联合治疗手足口病普通病例较使用其中单一药物效果显著。
Objective To compare the therapeutic effects of Lanqin oral solution and pidotimod tablets on common foot-mouth disease in children. Methods A total of 300 children with hand, foot and mouth disease were randomly divided into two groups: 100 mg and 100 mg each. The patients were randomly divided into two groups: Pidotimod tablets, Lan Qin oral pidotimod tablets treatment, observation of three groups of children with treatment. Results There was no significant difference in the antipyretic time, the time of herpes extinction, the regression time of hand-foot skin rash and the total effective rate between the two groups (P> 0.05). However, the combination therapy group (P <0.05), indicating that the combination therapy of both drugs can significantly promote fever and herpes zoster (P <0.05), and the difference between the two groups was statistically significant And the rash subsided, and improve the total efficiency. No obvious adverse reactions to both drugs. Conclusion The combination of Lanqin oral liquid and Pidotimod tablets in the treatment of common hand, foot and mouth disease than the common case of single drug effect is significant.