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目的 加深对儿童传染性单核细胞增多症（ｉｎｆｅｃｔｉｏｕｓ ｍｏｎｏｎｕｃｌｅｏｓｉｓ，ＩＭ） 的临床表现和实验室检查的认识，以减少误诊。方法 分析１９９１ 年５ 月至１９９７ 年１０ 月收治的６４ 例ＩＭ 的临床资料。结果 ＩＭ 临床表现复杂，本组误诊率为４５－３％ ，异形淋巴细胞≥０－１ 者３４ 例（ 占５３－１％ ），嗜异凝集反应（ＨＡ）阳性４６ 例（占７１－９％） ，ＶＣＡ－ＩｇＧ阳性率３９ 例（ 占６０－９％ ），查１１ 例患儿ＣＤ＋３ ，ＣＤ＋４ ，均较对照组低（ Ｐ 值均＜ ０－０１） 。结论 对持续高热、咽炎、皮疹、淋巴结或肝脾肿大者，可考虑ＩＭ，但须行上述血液学及免疫学检查综合诊断。
Objective To deepen the understanding of clinical manifestations and laboratory tests of infectious mononucleosis (IM) in children so as to reduce misdiagnosis. Methods Clinical data of 64 cases of IM admitted from May 1991 to October 1997 were analyzed. Results The clinical manifestations of IM were complicated. The rate of misdiagnosis in this group was 45-3%, 34 cases (53-1%) of abnormal lymphocytes ≥ 0-1, 46 cases (71-9%) of heterophilic agglutination reaction (HA) ), VCA-IgG positive rate of 39 cases (60-9%), check the 11 cases of children with CD +3, CD +4, were lower than the control group (P values <0-01). Conclusions IM may be considered for persistent hyperpyrexia, pharyngitis, rash, lymph nodes or hepatosplenomegaly, subject to the above comprehensive diagnostic hematology and immunological examinations.