众所周知 ,在酒精性肝损害的发病和进展上存在着性别差异 ,在饮用同量的情况下 ,女性较之男性却发生严重的肝损害。此种现象业经经胃管慢性乙醇大鼠模型 (Tsukamoto-French模型 )所证实 ,即模型动物的肝损害程度呈明显的雌雄差别。另一方面又有揭示 ,在酒精性肝损害的进展上 , It is well-known that there is a gender difference in the incidence and progression of alcoholic liver damage and that women suffer from severe liver damage compared to men in the same amount of drinking. This phenomenon was confirmed by a rat model of chronic alcoholism via the gastric tube (Tsukamoto-French model), in which the degree of liver damage in the model animals was significantly different between male and female. On the other hand, it has been revealed that on the progress of alcoholic liver damage,