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1988年的美国国际癌症协会提出了TBS分类法,从而出现了性质未定的意义不明的不典型鳞状细胞(atypical squamous cell of undetermined significance,ASCUS)的概念。根据宫颈细胞学TBS方法分类在美国每年约有2000万妇女被诊断为ASCUS,它有特定的诊断标准:细胞异常较反应性改变更明显,但尚未达到鳞状上皮内病变(squamou8 intra-epitheliallesion,SIL)的程度,可以是增生活跃的良性改变或潜在的恶性改变,不能对其进行明确分类而被命名。阴道脱落细胞学检查结果中ASCUS的出现为临床提供了模糊的信息,导致临床诊疗没有明确的模式。ASCUS是一种排除性诊断,
The 1988 IARC proposed the TBS taxonomy, resulting in the concept of an atypical squamous cell of undetermined significance (ASCUS) of undefined nature. According to the Cervical Cytology TBS method, about 20 million women are diagnosed with ASCUS each year in the United States and have specific diagnostic criteria: abnormalities of the cells are more pronounced than reactive changes but have not yet reached the level of squamous intraepithelial lesions SIL), which can be benign or potentially malignant changes that proliferate, can not be named for a clear classification. The appearance of ASCUS in vaginal cytology results provides ambiguous information for the clinic, resulting in no clear pattern of clinical diagnosis and treatment. ASCUS is a diagnosis of exclusion,