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目的探讨幽门螺杆菌(Hp)与胃食管反流病(GRED)的关系。方法将经内镜确诊的GERD患者50例及对照组轻度慢性浅表性胃炎患者70例,均行14C呼气试验及快速尿素酶法进行Hp检测。结果50例GERD患者Hp感染率为32.7%,70例对照组Hp感染率53.6%,GERD患者Hp感染率低于对照组,差异有统计学意义(P<0.05)。GERD患者各级之间Hp感染率差异无统计学意义(P>0.05)。结论Hp感染可能与胃食管反流病的发生有关。
Objective To investigate the relationship between Helicobacter pylori (Hp) and gastroesophageal reflux disease (GRED). Methods 50 patients with GERD diagnosed by endoscopy and 70 patients with mild chronic superficial gastritis in the control group were subjected to 14C breath test and rapid urease test for Hp. Results Hp infection rate was 32.7% in 50 cases of GERD patients and 53.6% in 70 cases of control subjects. Hp infection rate in GERD patients was lower than that in control group (P <0.05). There was no significant difference in Hp infection rate among all levels of GERD patients (P> 0.05). Conclusion Hp infection may be related to the occurrence of gastroesophageal reflux disease.