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目的 :探讨应用碘化油、化疗药、明胶海绵介入治疗晚期宫颈癌的临床效果。方法 :1996 -0 6～ 2 0 0 0 -0 3月 ,6 0例晚期宫颈癌分为两组 ,每一组 30 ,综合应用碘化油、化疗药、明胶海绵介入治疗组。首先注入 5 -Fu水化药 ,然后注入 3联化疗药加超液化碘油悬浮液 ,最后注入明胶海绵颗粒栓塞。第二组 30例放射治疗组。结果 :综合应用碘化油、化疗药、明胶海绵介入治疗组 ,30例中 2 4例症状完全缓解占 80 % ,4例明显缓解占 13 .3 % ,2例中度缓解占 6 .6 7% ;2 3例肿块完全消退占 76 .6 7% ,4例肿块缩小大于 5 0 %以上占 13 .33 % ,3例肿块缩小 5 0 %以下占 10 % ,2 6例Ⅱ期手术切除占 86 .6 7%。而放射治疗组 ,症状完全以及明显缓解共 2例占 6 .6 7% ,肿块完全以及明显消退为 0。胃肠道反应、血白细胞两组无明显差异。统计学处理有显著差异。结论 :综合应用碘化油、化疗药、明胶海绵介入治疗晚期宫颈癌是一种增加Ⅱ期手术切除率、提高疗效和生存质量的有效方法
Objective: To investigate the clinical effect of interventional treatment of advanced cervical cancer with iodized oil, chemotherapy drugs and gelatin sponge. Methods: Between March 1996 and June 2006, 60 cases of advanced cervical cancer were divided into two groups. Each group consisted of 30 cases. The iodized oil, chemotherapeutic agents and gelatin sponge were used in interventional therapy group. The first injection of 5 -Fu hydration drug, and then injected into the triple chemotherapy plus super-liquefied iodine oil suspension, and finally injected gelatin sponge particles embolization. The second group of 30 radiotherapy group. Results: With the combination of iodized oil, chemotherapeutic drug and gelatin sponge interventional treatment group, the complete remission rate of 24 cases was 80% in 30 cases, 13.3% in 4 cases and 6. 67 in 2 cases %; 23 cases of complete remission 76.67%, 4 cases of tumor size reduction more than 50% accounted for 13.33%, 3 cases of tumor size reduction of 50% or less accounted for 10%, 26 cases of stage II surgical resection accounted for 86.66 7%. Radiation therapy group, complete symptom and obvious relieve a total of 2 cases accounted for 6.76%, the tumor completely and obviously subsided to 0. Gastrointestinal reactions, white blood cells no significant difference between the two groups. There are significant differences in statistics. Conclusion: The combined application of iodized oil, chemotherapy drugs, gelatin sponge interventional treatment of advanced cervical cancer is an effective method to increase the rate of stage Ⅱ resection and improve the curative effect and quality of life