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本文总结我院近年来以吡喹酮治疗血吸虫病1761例的心电图前后对照观察,并以不同疗程(2d,1d,1次疗法)与不同剂量(总量分别为60mg/kg和40mg/g计算)分3组加以比较。发现在疗效相仿前提下,以总量40mg/kg,1d疗法心电图改变最少,安全度大,值得推广应用于门诊治疗慢性血吸虫病。同时,对吡喹酮诱发过早搏动的机理、剂量及服法略加讨论。
This article summarizes our hospital in recent years praziquantel treatment of schistosomiasis in 1761 cases of electrocardiogram before and after the control study, and different courses (2d, 1d, 1 therapy) with different doses (total were 60mg / kg and 40mg / g ) Divided into 3 groups to be compared. Found in the same effect on the premise of the total 40mg / kg, 1d therapy ECG changes least, safe, it is worth promoting the use of out-patient treatment of chronic schistosomiasis. At the same time, praziquantel induced premature beating mechanism, dosage and service slightly discussed.