间充质干细胞(Mesenchymal Stem Cells,MSCs)是一种具有多向分化潜能的成体干细胞。它不仅具有自我更新和体外扩增能力,还能在体内外有效抑制细胞和体液免疫应答,诱导免疫耐受。因此,MSCs已成为临床治疗免疫相关性疾病的极具前景的方法之一。本文主要针对MSCs的生物学特性、免疫调节功能以及在免疫治疗中的 Mesenchymal stem cells (MSCs) are adult stem cells that have multi-directional differentiation potential. It not only has the ability of self-renewal and in vitro amplification, but also can effectively inhibit cellular and humoral immune responses in vivo and in vitro, and induce immune tolerance. Therefore, MSCs have become one of the most promising methods for the clinical treatment of immune-related diseases. This article focuses on the biological characteristics of MSCs, immune regulatory function and in immunotherapy