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肺炎支原体(Mycoplasma pneumoniae,MP)通过诱导宿主细胞产生大量细胞内活性氧(Reactive Oxygen Species,ROS)及降低人体的免疫球蛋白IgG、IgA及IgM水平,引发人类多种呼吸道感染及肺外并发症。含有硒元素的谷胱甘肽过氧化物酶(Glutathion Peroxidase,GPx)及硫氧还蛋白还原酶(Thioredoxin Reductase,TR)能有效清除ROS,维持细胞内的还原态环境,帮助细胞抵抗肺炎支原体感染产生大量的ROS引起的氧化损伤及DNA损伤;同时,硒元素可提高机体免疫球蛋白水平,增强机体免疫功能,有效抵抗MP感染。
Mycoplasma pneumoniae (MP) induces multiple respiratory infections and extrapulmonary complications in humans by inducing host cells to produce large amounts of intracellular reactive oxygen species (ROS) and reducing the levels of human immunoglobulin IgG, IgA and IgM . Glutathion Peroxidase (GPx) and Thioredoxin Reductase (TR), which contain selenium, can effectively remove ROS and maintain the reduced environment inside the cells, helping the cells to resist Mycoplasma pneumoniae infection Produce a large number of ROS-induced oxidative damage and DNA damage; the same time, selenium can increase the body’s immune globulin levels, enhance immune function, effective against MP infection.