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目的:分析常熟市中医院药品不良反应(ADR)发生的特点,促进合理用药。方法:运用Microsoft OfficeExcel2003版电子表格和手工筛选方法,对2009年1月-2010年12月间收集的193份ADR报告,分别按患者性别、年龄,给药途径,药品分类,ADR累及器官或系统,以及常见ADR处理措施等方面进行分析、评价。结果:193例ADR报告中,抗感染药物导致ADR139例(72.02%),中药31例(16.06%);ADR累及器官或系统主要为皮肤及其附件149例和消化系统23例;给药途径主要为注射给药177例(91.71%)。结论:ADR的发生率与患者的年龄、给药途径、临床用药频率等密切相关,临床应予以重视。
Objective: To analyze the characteristics of adverse drug reaction (ADR) in Changshu Hospital of Traditional Chinese Medicine to promote rational drug use. Methods: 193 ADR reports collected from January 2009 to December 2010 were analyzed by patient’s sex, age, route of administration, drug classification, ADR involved organ or system, using Microsoft Office Excel 2003 version of the spreadsheet and manual screening method , As well as common ADR treatment measures and other aspects of analysis and evaluation. Results: Among the 193 ADR cases, anti-infectives caused 139 cases (72.02%) of ADRs and 31 cases of traditional Chinese medicines (16.06%). ADRs mainly involved the skin and its appendages, including 149 cases of skin and appendix and 23 cases of digestive system. 177 cases were injected for injection (91.71%). Conclusion: The incidence of ADR is closely related to the patient’s age, route of administration, frequency of clinical medication and so on, and should be paid more attention in clinic.