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目的观察不同服药时间对高血压患者降压效果的影响。方法将120例原发性高血压患者随机分为观察组与对照组各60例。观察组和对照组分别于晚7时和早上7时服用苯磺酸氨氯地平片,比较2组患者治疗前后血压水平和临床疗效。结果治疗前2组患者血压水平比较差异无统计学意义(P>0.05);治疗后2组患者血压水平均有所下降,且观察组低于对照组,差异均有统计学意义(P<0.01)。观察组的总有效率为86.67%明显高于对照组的70.00%,差异有统计学意义(P<0.05)。结论晚7时服用降压药较早7时的降压药效果好。通过对高血压患者的服药时间进行干预,可以有效提高降压药物的效果。
Objective To observe the effects of different medication time on hypertension in patients with hypertension. Methods 120 cases of essential hypertension were randomly divided into observation group and control group of 60 cases. The observation group and the control group were treated with amlodipine besylate at 7:00 pm and 7:00 am respectively. The blood pressure and clinical efficacy of the two groups were compared before and after treatment. Results There was no significant difference in blood pressure between the two groups before treatment (P> 0.05). After treatment, the blood pressure of the two groups decreased and the difference between the two groups was statistically significant (P <0.01) ). The total effective rate of the observation group was 86.67%, which was significantly higher than that of the control group (70.00%), the difference was statistically significant (P <0.05). Conclusions The antihypertensive effect of taking antihypertensive drugs as early as 7 o’clock after 7 o’clock is good. By taking medication time for patients with hypertension to intervene, can effectively improve the effect of antihypertensive drugs.