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目的观察采用低分子肝素钙合阿托伐他汀钙片治疗冠心病不稳定型心绞痛的治疗效果。方法观察组除常规用药外,加用低分子肝素钙5000u,2次/d,皮下注射,连用5d。对照组除常规用药外,另加普通肝素12500u+0.9%氯化钠注射液500m l静脉滴注,800单位/h,持续24h后改为7500u,2次/d皮下注射,连用5d。两组均加服阿托伐他汀钙20mg,每晚顿服1次,连用2周。结果观察组90例,显效70例,有效11例,无效9例,总有效率90%;对照组90例,显效67例,有效5例,无效18例,总有效率8 0%。结论在常规治疗基础上,低分子肝素钙联合阿托伐他汀治疗不稳定型心绞痛,症状缓解明显,总有效率高,而且安全可靠,有临床推广价值。
Objective To observe the therapeutic effect of low molecular weight heparin calcium and atorvastatin calcium on patients with unstable angina pectoris. Methods In addition to the conventional treatment group, the addition of low molecular weight heparin 5000u, 2 times / d, subcutaneous injection, once every 5 days. In addition to routine control, the control group was treated with ordinary heparin 12500u + 0.9% sodium chloride 500ml intravenous infusion, 800 units / h, continued for 24 hours and then changed to 7500u, 2 times / d subcutaneous injection, once every 5 days. Both groups were given atorvastatin calcium 20mg, Dayton night service 1, once every 2 weeks. Results The observation group of 90 cases, markedly effective in 70 cases, effective in 11 cases, ineffective in 9 cases, the total effective rate was 90%; 90 cases in the control group, markedly effective in 67 cases, effective in 5 cases, ineffective in 18 cases, the total effective rate was 80%. Conclusion On the basis of routine treatment, low molecular weight heparin combined with atorvastatin can relieve the symptoms of unstable angina pectoris. The total effective rate is high, and it is safe and reliable. It has clinical value of popularization.