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我国创制的解痉止痛新药——红古豆醇酯于1979年3月18日至21日由四川省科委、四川省化工局、四川省卫生局在成都主持召开鉴定会。出席会议的有北京、山东、湖南、青海、成都、重庆等省市的生产、科研、临床、教学、药检等31个单位的61名代表。会上总结交流了红古豆醇酯的化学半合成、药理、药物资源、临床应用、生产工艺、剂型改进和质量标准方面的实验研究和经验体会。红古豆醇酯是将从唐古特山莨菪根中提取的生物碱——红古豆碱还原为红古豆醇,再与苦杏仁酸酯化而制得的新药。其注射剂经数年临床应用,证明对肠
The new antispasmodic and painkilling drug, red coumarin ester, which was created in China, was held in Chengdu from March 18 to March 21, 1979 by the Sichuan Provincial Science and Technology Commission, the Sichuan Provincial Bureau of Chemical Industry, and the Sichuan Provincial Health Bureau. Attending the meeting were 61 delegates from 31 units of production, scientific research, clinics, teaching and drug inspections in Beijing, Shandong, Hunan, Qinghai, Chengdu and Chongqing. At the meeting, we summarized the experimental research and experience of the chemical semi-synthesis, pharmacology, drug resources, clinical application, production technology, dosage form improvement and quality standards of red crotonol esters. Red crotonol ester is a new drug obtained by reducing the alkaloid, red alkaloid extracted from the root of T. argenteus, to red crocodyl alcohol and then esterifying it with mandelic acid. After several years of clinical application of its injection, it proved