论文部分内容阅读
目的调查分析碳青霉烯类药物不敏感肺炎克雷伯菌院内感染原因,制订措施降低院内感染率。方法采用回顾性分析和前瞻性调查相结合的方法,选取10例对碳青霉烯类药物不敏感肺炎克雷伯菌阳性的住院患儿,依据其临床症状、细菌耐药检测结果、入院时检验结果等进行详细流行病学调查。结果 10例住院患儿中4例排除碳青霉烯类药物不敏感肺炎克雷伯菌感染,分析原因可能存在样本污染;4例确诊为对碳青霉烯类药物不敏感肺炎克雷伯菌感染,其中2例为院内感染、2例排除院内感染;另有2例不能明确诊断为对碳青霉烯类药物不敏感肺炎克雷伯菌感染。结论碳青霉烯类药物不敏感肺炎克雷伯菌是引起院内感染的重要致病菌,应对其引起医院的足够重视。应坚持检验与调查相结合,寻根溯源,注重各接触环节隔离消毒,加强工作人员培训,提高院内感染控制意识。
Objective To investigate the causes of nosocomial infection of Klebsiella pneumoniae insensitive to carbapenems and to develop measures to reduce the nosocomial infection rate. Methods Retrospective analysis and prospective investigation combined with the method of selection of 10 cases of carbapenems insensitive Klebsiella pneumoniae hospitalized children, according to their clinical symptoms, bacterial resistance test results, admission Test results and other detailed epidemiological investigation. Results Of 10 hospitalized children, 4 cases were excluded from carbapenems-insensitive Klebsiella pneumoniae infection, the possible causes of sample contamination were analyzed. Four cases were diagnosed as carbapenem-insensitive Klebsiella pneumoniae Infections, 2 were nosocomial infections, 2 patients were excluded nosocomial infection; the other 2 patients can not be diagnosed as carbapenems insensitive to Klebsiella pneumoniae infection. Conclusion carbapenems insensitive Klebsiella pneumoniae is an important pathogenic bacteria causing nosocomial infection, which should pay enough attention to the hospital. Should adhere to the combination of inspection and investigation, root tracing, pay attention to the isolation and disinfection of contact links, to strengthen staff training and improve awareness of infection control in the hospital.