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目的 :证实河北省恙虫病的存在。方法 :对可疑病人进行调查、采血 ,用血清学方法检测病人血清抗体并分型。结果 :14例发热病人中的 13例被诊断为恙虫病 ,确诊率为 92 .86 %。患者均为成年人 ,年龄在 32～ 6 9岁之间 ,男性 4例 ,女性 9例。发病时间为 1997年 10月 1～ 2 0日。病人血清OXk抗体阳性率为 10 0 % ,GMT为 1∶92 6 .6 ;恙虫病立克次氏体IgG抗体阳性率为92 .3% ,GMT为 1∶94 1.2 ;IgM抗体阳性率为 84 .6 % ,GMT为 1∶1546 .4。对病人血清标本进行血清学分型 ,证实为恙虫病Gilliam血清型。结论 :河北省太行山区首次被证实有恙虫病病例存在。有关本病的流行因素和特征正在研究中
Objective: To confirm the existence of tsutsugamushi disease in Hebei Province. Methods: Suspicious patients were investigated and blood samples were collected. Serum antibodies were detected by serological methods and were divided into two groups. Results: Thirteen of 14 febrile patients were diagnosed as tsutsugamushi disease with a diagnosis rate of 92.86%. All patients were adults, aged 32 to 69 years, 4 males and 9 females. The onset time for October 1997 1 ~ 20 days. The positive rate of serum OXk antibody was 100% and the GMT was 1:92 6 .6. The positive rate of Rickettsia rickettsi IgG antibody was 92.3%, the GMT was 1:94 1.2, the positive rate of IgM antibody was 84 .6%, GMT 1:1546 .4. Serological typing of patients with serum samples, confirmed as tsutsugamushi Gilliam serotypes. Conclusion: The first case of tsutsugamushi was confirmed in the Taihang Mountains in Hebei Province. The epidemiological factors and characteristics of this disease are under study