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目的探讨血栓通治疗缺血性脑血管疾病的临床疗效。方法选取贵阳市第二人民医院2015年3月—2016年7月收治的缺血性脑血管疾病患者120例,随机将患者分为对照组与观察组,各60例。两组患者均给予急性期降血压、脱水和降低颅内压等治疗,观察组患者在此基础上给予血栓通治疗,两组患者均持续治疗15 d。比较两组患者临床疗效、神经功能缺损评分、生活自理能力评价量表(ADL)评分、认知功能量表(MMSE)评分、生存质量测定量表(WHO-QOL)(生理功能、环境、社会关系、心理状态、独立性、精神/宗教)评分、血液流变学指标(全血黏度、血浆黏度、红细胞聚集指数)。结果观察组患者临床疗效优于对照组(P<0.05)。观察组患者神经功能缺损评分低于对照组,ADL评分、MMSE评分高于对照组(P<0.05)。观察组患者生理功能、环境、社会关系、心理状态、独立性、精神/宗教评分高于对照组(P<0.05)。观察组患者全血黏度、血浆黏度及红细胞聚集指数低于对照组(P<0.05)。结论血栓通治疗缺血性脑血管疾病的临床疗效确切,可有效减轻患者神经功能缺损程度,改善血液流变学,提高认知功能和生活自理能力,改善其生存质量。
Objective To investigate the clinical efficacy of Xueshuantong in treating ischemic cerebrovascular diseases. Methods A total of 120 patients with ischemic cerebrovascular disease who were admitted to the Second People’s Hospital of Guiyang from March 2015 to July 2016 were randomly divided into control group and observation group, with 60 cases in each group. Both groups were given acute hypotensive blood pressure, dehydration and reduce intracranial pressure and other treatment, the observation group were given on this basis Xueshuantong treatment, both groups were treated for 15 days. The clinical efficacy, neurological deficit score, ADL score, MMSE score and WHO-QOL (physiological function, environment and society) were compared between the two groups Relationship, state of mind, independence, spiritual / religious), hemorheology (whole blood viscosity, plasma viscosity, erythrocyte aggregation index). Results The clinical efficacy of the observation group was better than that of the control group (P <0.05). The score of neurological deficit in observation group was lower than that in control group, ADL score and MMSE score were higher than those in control group (P <0.05). The physical function, environment, social relations, mental status, independence and mental / religious scores of the observation group were higher than those of the control group (P <0.05). The whole blood viscosity, plasma viscosity and erythrocyte aggregation index in the observation group were lower than those in the control group (P <0.05). Conclusion Xueshuantong is effective in treating ischemic cerebrovascular diseases. It can effectively reduce the degree of neurological deficits, improve hemorrheology, improve cognitive function and life self-care ability, and improve its quality of life.