论文部分内容阅读
A total of 436 goat samples from twenty-six populations were scanned for single nucleotide polymor-phisms (SNPs) in 5’UTR of goat MSTN gene using sequen-cing and the polymerase chain reaction technique combined with restriction enzyme fragment length polymorphism (PCR-RFLP). The deletion of TTTTA found in 5’UTR of goat MSTN gene was conserved in different species and might be a unique mutation in goats. The Foreign Group and the Boer Goat backcrossed offspring had the highest and smallest genetic diversity of this mutation respectively, and also with the smallest and highest heterozygosity defi-ciency respectively. The genetic diversity of this mutation for the South Group of Chinese indigenous goat breeds was higher than that of the North Group, and the South Group had the smaller heterozygosity deficiency than the North Group. The estimated marginal means based on the modified population marginal mean and pairwise com-parison between significant pairs showed that there was a trend that genotype AA had a significant effect on body weight and size from birth to four-month old (P<0.05 or P<0.01). It could be inferred that the deletion of TTTTA in 5’UTR of goat MSTN gene had a significant effect on body weight and size.