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目的评价B型尿利钠肽(BNP)在器质性心脏病伴肺源性呼吸困难中的价值。方法196例伴有肺源性呼吸困难的器质性心脏病患者依据BNP分为心功能不全组和心力衰竭组,对两组BNP进行测定并比较。结果无BNP,初步诊断正确率76%,结合BNP初步诊断正确率95%。依据BNP水平分组,心功能不全组110例,平均BNP水平(162±43)pg/ml,心力衰竭组86例,平均BNP水平(1020±242)pg/ml,两者差异有统计学意义。结论对肺源性呼吸困难伴器质性心脏病患者,BNP测定可用于权衡心功能不全对呼吸困难的影响,对指导临床诊疗有重要意义。
Objective To evaluate the value of B-type natriuretic peptide (BNP) in patients with organic heart disease with pulmonary-derived dyspnea. Methods A total of 196 patients with organic heart disease with pulmonary dyspnea were divided into heart failure group and heart failure group according to BNP. BNP in both groups were measured and compared. Results No BNP, the correct rate of initial diagnosis of 76%, combined with BNP preliminary diagnosis of correct rate of 95%. According to the level of BNP, 110 patients with cardiac dysfunction, mean BNP level (162 ± 43) pg / ml, heart failure group with 86 patients and mean BNP level (1020 ± 242) pg / ml had statistical significance. Conclusion BNP can be used to weigh the impact of cardiac insufficiency on dyspnea in patients with pulmonary-derived dyspnea and organic heart disease, which is of great significance in guiding the clinical diagnosis and treatment.