论文部分内容阅读
目的:探讨~(18)F-FDG PET/CT显像在骨肉瘤诊断中的影像学特征。方法:对在2005年1月至2011年5月在本院就诊经病理检查确诊的原发性骨肉瘤患者行~(18)F-FDG PET/CT全身显像,采用感兴趣区(ROI)技术计算肿瘤病灶的SUVmax,同时分析同机CT扫描图像的影像学特点,着重研究肿瘤新生骨及软组织肿块特点。结果:10例原发性骨肉瘤患者的原发病灶均位于干骺端,其中位于股骨下端6例,肱骨上端2例,股骨颈和胫骨上段各1例,1例发现有“跳跃性转移灶”。同机CT影像表现为骨质破坏、肿瘤骨、骨膜反应或骨膜三角和软组织肿块。其中,肿瘤骨对~(18)F-FDG呈低摄取,而非瘤骨区或软组织肿块对~(18)F-FDG摄取明显增高。“跳跃性转移灶”呈明显~(18)F-FDG高摄取。结论:~(18)F-FDG PET/CT实现了对原发性骨肉瘤解剖结构改变和代谢变化的优势互补,对骨肉瘤的诊断及治疗提供了依据。
Objective: To investigate the imaging features of ~ (18) F-FDG PET / CT in the diagnosis of osteosarcoma. Methods: We performed 18 F-FDG PET / CT whole body scintigraphy in primary osteosarcoma diagnosed by pathology in our hospital from January 2005 to May 2011. The ROI (Region of Interest) Technique to calculate the SUVmax of tumor focus, and analyze the imaging characteristics of the same CT scan images, focusing on the characteristics of tumor bone and soft tissue mass. Results: The primary lesions in 10 cases of primary osteosarcoma all located in the metaphysis, including 6 cases in the lower femur, 2 cases in the upper end of the humerus, 1 case in the upper part of the femoral neck and tibia, 1 case of “jumpy metastasis” kitchen". CT imaging with the same machine showed bone destruction, tumor bone, periosteal reaction or periosteal trigone and soft tissue mass. Among them, tumorous bone showed a low uptake of ~ (18) F-FDG, whereas the uptake of ~ (18) F-FDG was significantly higher in non-tumorous bone or soft tissue mass. Jumping metastases showed a significant uptake of (18) F-FDG. Conclusion: ~ (18) F-FDG PET / CT has the advantages of complementarity in the anatomic changes and metabolic changes of primary osteosarcoma, and provides a basis for the diagnosis and treatment of osteosarcoma.