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目的探讨妊娠期糖尿病孕妇系统管理对母婴妊娠结局的影响。方法收集我院2008年1月～2009年12月诊断的妊娠期糖尿病病例381例,分为系统管理组241例和未管理组140例。比较两组病例妊娠并发症及围生儿结局。结果妊娠期糖尿病未管理组子痫前期、羊水过多、早产的发生率较系统管理组明显升高(P<0.05);巨大儿、新生儿高胆红素血症、、新生儿低血糖、心肌病变(包括先天性心脏病)、新生儿呼吸窘迫综合征(NRDS)及胎粪吸入综合征(MAS)的发生率亦明显高于系统管理组(P<0.01),而新生儿窒息率的差异无显著性意义(P>0.05)。结论妊娠期糖尿病与妊娠并发症密切相关,未系统管理及血糖未控制者围生儿结局不良,应加强对妊娠期糖尿病孕妇的孕期管理。
Objective To investigate the effect of systemic management of pregnant women with gestational diabetes on maternal and fetal pregnancy outcomes. Methods 381 cases of gestational diabetes mellitus diagnosed in our hospital from January 2008 to December 2009 were collected and divided into 241 cases in system management group and 140 cases in unmanaged group. Pregnancy complications and perinatal outcome were compared between the two groups. Results The incidence of preterm preterm and preterm birth in pre-eclampsia and non-pre-eclampsia patients in gestational diabetes mellitus group was significantly higher than that in the systemic management group (P <0.05). In macrosomia, neonatal hyperbilirubinemia, neonatal hypoglycemia, The incidence of cardiomyopathy (including congenital heart disease), neonatal respiratory distress syndrome (NRDS) and meconium aspiration syndrome (MAS) was also significantly higher than that of the systemic management group (P <0.01), while neonatal asphyxia There was no significant difference (P> 0.05). Conclusions Gestational diabetes mellitus is closely related to pregnancy complications. Without systematic management and poor outcome of perinatal children with uncontrolled blood glucose, pregnant women with gestational diabetes mellitus should be better managed during pregnancy.