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目的观察达克普隆+阿莫西林+甲硝唑三联一周疗法抗幽门螺杆菌(HP)感染的治疗效果,并与胶体铋+阿莫西林+甲硝唑两周疗法相对比,比较两个方案的HP根治率。方法选择63例病人,随机分为2组,A组治疗方法为达克普隆30mgBic、阿莫西林0.5Bid、甲硝唑0.4Bid,疗程一周;B组治疗方法为胶体次枸橼酸铋240mgBid、阿莫西林0.5Bid、甲硝唑0.4Bid疗程二月。患者停药后一月,用快速尿素酶(14)~C—尿素呼气试验复查HP。结果HP根治率:A组为87.5%,B组为87.1%。结论达克普隆三联和铋剂三联疗效相同,但达克普隆疗效短,服用抗生素少,病人依从住比较好,是一种比较好的方案。
Objective To observe the therapeutic effect of daclopron, amoxicillin and metronidazole combined with one week therapy against Helicobacter pylori (HP) infection and to compare with two weeks therapy of bismuth colloid + amoxicillin + metronidazole Program of HP cure rate. Methods Sixty-three patients were randomly divided into two groups. The treatment of group A was donepronone 30 mg Bic, amoxicillin 0.5 Bid and metronidazole 0.4 Bid for one week. The treatment of group B was colloidal citric acid Bismuth 240mgBid, amoxicillin 0.5Bid, metronidazole 0.4Bid treatment February. One month after discontinuation, the patients were reexamined with rapid urease (14) C-urea breath test. Results The cure rate of HP was 87.5% in group A and 87.1% in group B. Conclusions Triplex and bismuth triadimefon have the same effect, but the efficacy of daclopron is short, taking less antibiotics and better patient compliance, which is a better solution.