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目的:探讨马来酸桂哌齐特联合腹部带蒂皮瓣治疗手及前臂皮肤软组织烧伤缺损的临床效果。方法:选取我院2011年2月-2013年2月收治的68例手及前臂皮肤软组织烧伤缺损患者作为观察组,行马来酸桂哌齐特结合腹部带蒂皮瓣治疗,另选择同期接受股前外侧皮瓣修复治疗的50例患者为对照组。观察并比较两组患者皮瓣修复效果以及神经功能烧伤缺损评分。结果:观察组患者皮瓣存活率高于对照组,差异具有统计学意义(P<0.05);观察组皮瓣感染率低于对照组,差异具有统计学意义(P<0.05);观察组皮瓣断蒂时间及神经功能烧伤缺损评分均低于对照组,差异具有统计学意义(P<0.05)。结论:马来酸桂哌齐特结合腹部带蒂皮瓣治疗具有皮瓣存活率高、神经功能恢复良好,术后恢复快等特点,值得临床推广应用。
Objective: To investigate the clinical effect of cinepazide maleate combined with abdominal pedicled skin flap in the treatment of skin and soft tissue injury of forearm and forearm. Methods: Sixty-eight patients with forearm skin and soft tissue defects who were treated in our hospital from February 2011 to February 2013 were selected as the observation group. The patients were treated with cinepazide maleate and abdominal pedicle flap. 50 cases of anterolateral skin flap repair treatment for the control group. The skin flap repair and neurological deficit score of the two groups were observed and compared. Results: The survival rate of flap in observation group was higher than that in control group (P <0.05). The infection rate of flap in observation group was lower than that in control group (P <0.05) The time of pedicel pedicel injury and the score of neurological burn injury were lower than the control group, the difference was statistically significant (P <0.05). Conclusion: Cinepazide maleate combined with abdominal pedicle flap has the characteristics of high survival rate of skin flap, good neurological function recovery and rapid recovery after operation, which is worthy of clinical application.