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目的探讨胃底腺息肉(fundic gland polyps,FGPs)患者的临床、内镜及病理特点。方法对2009年1月~2012年5月在我院胃镜检查诊断FGPs的临床资料进行分析。结果检出FGPs 42例,检出率为0.8%,占胃息肉的27.45%,临床表现缺乏特异性,息肉主要分布于胃底及胃体,形态以山田Ⅱ型为主,多数<0.5 cm,多发息肉多见,组织学以胃底腺大量增生为主体,无急性炎症、肠化及异型增生表现。结论 FGPs有较高的检出率,部分与长期口服质子泵抑制剂(PPl)有关,与幽门螺杆菌(Hp)感染无明显相关性,预后良好。
Objective To investigate the clinical, endoscopic and pathological characteristics of patients with fundic gland polyps (FGPs). Methods The clinical data of FGPs diagnosed by gastroscopy in our hospital from January 2009 to May 2012 were analyzed. Results 42 cases of FGPs were detected. The detection rate was 0.8%, accounting for 27.45% of the gastric polyps. The clinical manifestations were lack of specificity. The polyps were mainly distributed in the fundus and stomach, and the morphology was dominated by Yamada type II, most of which was <0.5 cm. Multiple polyps are more common, and histology is mainly based on the massive proliferation of gastric glands without any manifestations of acute inflammation, intestinal metaplasia, and dysplasia. Conclusion The high detection rate of FGPs is partly related to the long-term oral proton pump inhibitor (PPl) and no significant correlation with Helicobacter pylori (Hp) infection. The prognosis is good.