论文部分内容阅读
目的:综述近年胰高血糖素样肽1及其类似物的研究进展,为糖尿病心血管病变的临床防治提出新的思路。方法:通过检索近10余年的相关文献,总结胰高血糖素样肽1及其类似物对糖尿病心血管病的作用及其相关机制。结果结论:目前研究提示胰高血糖素样肽1除了可以有效降低血糖以外,还通过多种机制影响心脏和血管的功能,此类活性物质以其独特的作用机制,为糖尿病心血管病变的治疗掀开新的一页。
OBJECTIVE: To summarize the research progress of glucagon-like peptide 1 and its analogues in recent years, and to put forward new ideas for the clinical prevention and treatment of diabetic cardiovascular disease. Methods: By searching the relevant literature of nearly 10 years, the effects of glucagon-like peptide 1 and its analogues on diabetic cardiovascular disease and its related mechanisms were summarized. Conclusions: The current study suggests that glucagon-like peptide 1 can not only effectively lower blood glucose, but also affect the function of the heart and blood vessels through a variety of mechanisms. This kind of active substances is a unique mechanism of action for the treatment of diabetic cardiovascular diseases Open a new page.