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目的观察两种不同雾化吸入方案治疗支气管哮喘的疗效。方法选择我院支气管哮喘患者151例,随机分为对照组和试验组,对照组75例,试验组76例。对照组使用沙丁胺醇(每次150μg/kg)、溴化异丙托品(每次250μg)雾化吸入治疗,5~10 min/次,2~3次/d。试验组加用布地奈德(每次100μg/kg)雾化吸入治疗,5~10 min/次,2~3次/d。均连续治疗5 d。结果试验组和对照组的总有效率比较,试验组优于对照组,其差异有统计学意义(P<0.05)。结论布地奈德是常见的吸入用糖皮质激素,在支气管哮喘的治疗中加用布地奈德雾化吸入从而增强抗炎作用,可能是取得较好疗效的因素。
Objective To observe the effects of two different inhalation protocols on bronchial asthma. Methods 151 cases of bronchial asthma in our hospital were randomly divided into control group and experimental group, 75 cases in control group and 76 cases in experimental group. Patients in the control group were treated with salbutamol (150 μg / kg each time) and ipratropium bromide (250 μg each) for 5 to 10 min / 2 to 3 times / d. Test group plus budesonide (each 100μg / kg) inhalation therapy, 5 ~ 10 min / time, 2 ~ 3 times / d. Continuous treatment of 5 d. Results The total effective rate of the experimental group and the control group was significantly higher than that of the control group (P <0.05). Conclusions Budesonide is a common inhaled glucocorticoid used in the treatment of bronchial asthma with budesonide inhalation to enhance anti-inflammatory effect may be to obtain better efficacy of the factor.