本文报告经皮穿刺三叉神经半月池甘油注射治疗三叉神经痛３１０例，取得较好疗效。经半年～９年随访，远期疗效：完全止痛为８０．６％，明显好转１３．５％。复发６．５％，总有效率为９０．６６％，其中无效占２．５的％，穿刺失败３．２％。作者根据自己的实践经验，结合文献，就如何提高疗效等问题进行讨论。 This article reports percutaneous trigeminal nerve injection of meniscal glycerol in 310 cases of trigeminal neuralgia, and achieved good results. After six months to 9 years follow-up, long-term efficacy: complete pain relief was 80.6%, significantly improved 13.5%. Relapse of 6.5%, the total effective rate was 90.66%, of which 2.5% of ineffective, puncture failure of 3.2%. According to his own practical experience, combined with the literature on how to improve the efficacy and other issues for discussion.