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对HBcAg阳性病人血清进行检测,并观察e系统及ALT与之关系,结果表明:HBcAg阳性病人ALT明显升高,与HBeAg阳性病人ALT成正相关,与抗HBe阳性病人ALT成负相关。同时乙肝患者HBcAg与HBeAg同时阳性率远高于HBcAg阳性与HBeAg阴性和HBcAg阳性与抗HBe阳性的组合。提示:反映肝细胞损害程度的ALT的升高和HBeAg、HBcAg同时阳性成正相关、临床上可考虑乙肝患者HBcAg、HBeAg阳性和ALT异常作为HBV复制指标。
The serum of patients with HBcAg positive was detected, and the relationship between e system and ALT was observed. The results showed that ALT in HBcAg positive patients was significantly increased, positively correlated with ALT in HBeAg positive patients and negatively correlated with ALT in HBeAg positive patients. At the same time, the positive rate of HBcAg and HBeAg in hepatitis B patients is much higher than the combination of HBcAg positive and HBeAg negative and HBcAg positive and anti HBe positive. Hint: The increase of ALT, which reflects the extent of hepatocellular damage, is positively correlated with the positive of HBeAg and HBcAg. HBcAg, HBeAg positive and abnormal ALT may be considered clinically as indicators of HBV replication.