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目的探讨脑外伤导致脑梗死的发病机制及治疗方法。方法总结我院26例外伤性脑梗死的临床特点,治疗方法及预防措施。结果创伤性大面积脑梗死的发病机制与血液流变学变化、血管内皮损伤、血管的解剖学特点及自由基引起的生物反应等因素有关。本组患者死亡8例,重残7例,中残8例,良好3例。结论脑外伤后脑梗死发病机制复杂,应根据患者病情因人而异,采取适当的综合治疗方法,进行有针对性的治疗才能获得比较满意的治疗效果。
Objective To investigate the pathogenesis and treatment of cerebral infarction caused by traumatic brain injury. Methods The clinical features, treatment and preventive measures of 26 cases of traumatic cerebral infarction in our hospital were summarized. Results The pathogenesis of traumatic massive cerebral infarction was related to the changes of hemorheology, vascular endothelial injury, the anatomic features of blood vessels and the biological responses induced by free radicals. The group of patients died in 8 cases, severe disability in 7 cases, 8 cases of residual, good in 3 cases. Conclusions The pathogenesis of cerebral infarction after traumatic brain injury is complex and should be based on the patient’s condition varies from person to person. Appropriate comprehensive treatment methods and targeted treatment can achieve satisfactory therapeutic effects.