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在传统盲探穿刺的基础上，近年来提出一种新的压力波形监测方法用于硬膜外麻醉。相比较于临床普遍采用的阻力消失法以及超声引导、计算机断层扫描、介入造影等新兴的辅助硬膜外麻醉的穿刺方法，大量研究表明压力波形监测方法可作为硬膜外麻醉穿刺成功的客观指征，可全程实时监测硬膜外麻醉过程，安全可靠，简便实用。文章回顾压力波形监测方法在硬膜外麻醉应用的原理，对硬膜外麻醉穿刺置管过程中的压力波形特点及其临床应用进行综述。压力波形监测方法为硬膜外麻醉提供了一种简单的辅助手段，可以区分阻力消失法的真阳性和假阳性。“,”Based on traditional blind puncture used in epidural anesthesia, a new pressure waveform monitoring method has been proposed to evaluate the success of epidural anesthesia in recent years. Compared with the commonly used epidural anesthesia puncture methods, such as the loss-of-resistance technique and other new techniques, for example, ultrasonography, computed tomography, and interventional angiography, a large number of studies have shown that the pressure waveform is an objective indicator of epidural anesthesia. Pressure-waveform method can timely monitor the epidural anesthesia process. It is safe, reliable, simple and practical. This article reviews the principle of the pressure waveform in the application of epidural anesthesia and summarizes the characteristics of the pressure waveform and its clinical application during the puncture and catheterization of the epidural anesthesia. The pressure waveform provides a simple auxiliary method for epidural anesthesia, which can distinguish the true positive and false positive of resistance of loss.