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使用 IUCD 的妇女出现一定百分比月经过多的原因尚不明了,有报告在鼠和妇女放置 IUCD 的子宫内膜过氧化氢酶的活性水平显著高于未置 IUCD的对照组,似乎月经过多与过氧化氢酶使子宫内膜的过氧化氢(H_2O_2)过度生成,或其它内环境稳定性的机制相关。众所周知维生素 E 可控制组织脂质过度氧化,是身体的抗氧化物与游离基的收集剂,故作者等将维生素 E 对放置 IUCD 的妇女作了临床试用并取得初步结果。从门诊随机选择病人51例,均系放置 IUCD 后因月经过多而求医者。45％是放置后损伤性出血,其余55％主诉在放置 IUCD 后6～33个月出现难以
The reasons for the presence of a certain percentage of women who use IUCD for menorrhagia are unknown. The level of activity of endometrial catalase reported in IUCD in rats and women was significantly higher than that in controls without IUCD, and it seems that menorrhagia and Catalase causes the overproduction of hydrogen peroxide (H 2 O 2) in the endometrium, or other mechanisms of homeostasis. It is well-known that vitamin E can control tissue lipid over-oxidation, is the body’s antioxidant and free radical collection agent, so the author will vitamin E for placement of IUCD clinical trials and achieved preliminary results. Randomly selected patients from the clinic in 51 cases, were placed after IUCD due to menorrhagia and seek medical treatment. 45% were post-placement traumatic bleeding, and the remaining 55% complained of difficulty 6 to 33 months after placement of IUCD