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以核孔滤筛法测定由55例急性脑出血患者静脉血制备的标准红细胞悬液和标准红白细胞悬液的滤过指数(IndexofFiltration,IF)。比较以神经功能缺损评分标准所分成的轻、中、重3组上述两种悬液的IF,结果发现前者的IF在脑出血各组及对照组间无显著差异,而后者则差异极为显著(F检验,P<0.01)。标准红白细胞悬液的IF与脑出血量及临床神经功能缺损评分呈正相关。提示急性脑出血白细胞变形性测定可作为判断临床神经功能缺损、估计脑出血量和评价疾病预后的一个有意义的指标。
The index of filtration (IF) of standard erythrocyte suspensions and standard erythrocytes suspensions prepared from venous blood of 55 patients with acute cerebral hemorrhage was determined by nuclear pore filter. The comparison of the IF of the above two suspensions of light, medium and heavy groups divided by the score of neurological deficit showed no significant difference in the former IF between the groups of cerebral hemorrhage and the control group, but the latter was extremely significant F test, P <0.01). The IF of standard erythroblast cell suspension was positively correlated with the amount of cerebral hemorrhage and clinical neurological deficit score. Prompt determination of acute cerebral hemorrhage white blood cell deformability can be used as a judge of clinical neurological deficit, assess the amount of cerebral hemorrhage and evaluate the prognosis of the disease a meaningful indicator.