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目的探讨结核性脑膜炎的临床特征,并对其诊断和治疗方法进行总结。方法选取2014年2月~2016年4月我院收治的结核性脑膜炎患者120例作为研究对象,对其临床体征及症状、实验室检查结果合诊断及治疗资料进行总结分析。结果在120例结核性脑膜炎患者中,以发热(91.67%)、头痛(76.67%)、恶心、呕吐(62.50%)及脑膜刺激征阳性(63.33%)最为常见,且多存在不同程度脑脊液改变;早期四联综合抗结核方案,可有效对患者的病情发展进行控制,总治疗有效率达85.83%。结论结核性脑膜炎患者早期临床特征及脑脊液改变缺乏典型性,应根据患者的病原学检查结果,并结合其影像学检查和颅外结核病灶分布情况对其作出综合诊断,一经确诊应尽快开展综合抗结核治疗。
Objective To investigate the clinical features of tuberculous meningitis and to summarize its diagnosis and treatment. Methods A total of 120 patients with tuberculous meningitis in our hospital from February 2014 to April 2016 were selected as the research object, and their clinical signs and symptoms, laboratory diagnosis and treatment data were summarized and analyzed. Results Of 120 patients with tuberculous meningitis, fever (91.67%), headache (76.67%), nausea and vomiting (62.50%) and positive meningeal irritation (63.33%) were most common and there were many cerebrospinal fluid changes ; Early quadruple combined anti-TB program, which can effectively control the progression of the patient’s condition, the total effective rate was 85.83%. Conclusion The early clinical features of tuberculous meningitis and the lack of typical cerebrospinal fluid changes should be based on the patient’s etiological examination results, combined with its imaging findings and the distribution of extracranial tuberculosis to make a comprehensive diagnosis of it, once diagnosed should be comprehensive as soon as possible Anti-TB treatment.