目的:观察中西医结合治疗阴虚血热型特发性血小板减少性紫癜(ITP)的疗效与优势。方法:选择阴虚血热型ITP的患者97例,分为中西医结合治疗组、中药对照组及西药对照组,经治疗1～2个疗程后观察各组的疾病疗效、中医证候疗效以及3组出现的不良反应发生率。结果:中西医结合治疗组总有效率为84.3%,均优于单纯中药组和西药组;中医证候改善总有效率为87.5%,明显优于西药对照组(31.4%),有统计学意义。中西医结合治疗组不良反应发生率与中药组相当,显著低于西药对照组。结论:中西医结合治疗阴虚血热型ITP的疗效优于单纯中药组和西药组,其中药对于激素可起到增效减毒的作用。 Objective: To observe the efficacy and advantages of integrated traditional Chinese and western medicine in the treatment of idiopathic thrombocytopenic purpura (ITP). Methods: One hundred and ninety-seven patients with ITP of deficiency of blood and heat type were divided into three groups: Integrative Medicine Group, Traditional Chinese Medicine Control Group and Western Medicine Control Group. After treatment for 1-2 months, the curative effect of each group, Adverse reactions occurred in 3 groups. Results: The total effective rate of treatment group was 84.3%, which were better than those of pure traditional Chinese medicine group and western medicine group. The total effective rate of TCM syndrome improvement was 87.5%, which was significantly better than western medicine control group (31.4%), with statistical significance . The incidence of adverse reactions in the combination of traditional Chinese and Western medicine treatment group and the traditional Chinese medicine group was significantly lower than the western medicine control group. Conclusion: The curative effect of traditional Chinese medicine and western medicine on treating ITP with deficiency of blood and heat type is better than that of traditional Chinese medicine group and western medicine group. The medicine can play a synergistic and attenuating effect on hormones.