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目的探讨睾丸间质细胞瘤的诊断和治疗经验。方法报告1例双侧睾丸间质细胞瘤患者的临床资料并文献复习。结果根据患者临床表现及相关检查,术前诊断考虑为双侧睾丸间质细胞瘤,术中快速冰冻病理检查示双侧睾丸间质细胞瘤,行睾丸肿瘤剜除术。术后随访6个月未见肿瘤复发或转移。结论睾丸间质细胞瘤是一种较为罕见的睾丸肿瘤。术前诊断较为困难,睾酮、雌二醇等性激素水平升高及男性乳房发育等症状对睾丸间质细胞瘤的诊断有重要意义,确诊仍需依赖病理组织学检查。传统的手术方法采用根治性睾丸切除术,然而对于青春期前患者、双侧睾丸间质细胞瘤等患者,可以施行保留睾丸的肿瘤剜除术。
Objective To explore the diagnosis and treatment of testicular stromal tumor. Methods A case of bilateral testicular stromal tumor was reported and reviewed. Results According to the clinical manifestations and related tests, preoperative diagnosis was considered as bilateral testicular stromal tumor, rapid intraoperative frozen pathological examination showed bilateral testicular stromal tumor, testicular tumor resection. No tumor recurrence or metastasis was observed after 6 months of follow-up. Conclusion Testicular stromal tumor is a rare testicular tumor. Preoperative diagnosis is more difficult, elevated testosterone, estradiol and other sex hormones and male breast development and other symptoms of testicular stromal tumor is of great significance, the diagnosis still need to rely on histopathological examination. Conventional surgical procedures using radical orchidectomy, however, for pre-puberty patients, bilateral testicular stromal tumor and other patients, can be performed to retain the testis tumor removal surgery.